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Kan indtagelse af Liponsyre og Carnitine forhindre Parkinson

Redigeret 28 august, 2008, 18:24 i Parkinsons sygdom
Fra dette link:
http://www.ncbi.nlm.nih.gov/pubmed/1862 ... t=Abstract

Og fra denne artikel kan det læses, at Liponsyre og Carnitine formodentlig har en effekt på Parkinsons Sygdom.

Topic: Alpha-Lipoic Acid and Acetyl-L-Carnitine in the Prevention of Parkinson's Disease
Keywords: PARKINSON'S DISEASE - Alpha-Lipoic Acid, R-Alpha-Lipoic Acid, Lipoic Acid, Acetyl-L-Carnitine, L-Carnitine
Reference: "Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease," Zhang H, Jia H, et al, J Cell Mol Med, 2008; [Epub ahead of print]. (Address: Jiankang Liu, PhD, Institute for Brain Aging and Dementia, University of California, 1261 Gillespie Neuroscience Research Facility Irvine, CA 92697-4540, CA, USA. E-mail: j.liu@uci.edu ).
Summary: In a study involving a rotenone-induced cellular model of Parkinson's disease (PD), 4-week pre-treatment with a combination of R-alpha-lipoic acid (LA) and acetyl-L-carnitine (ALC) was found to protect SK-N-MC human neuroblastoma cells against rotenone-induced mitochondrial dysfunction, oxidative damage, and accumulation of alpha-synuclein and ubiquitin, and to increase mitochondrial biogenesis and decrease production of reactive oxygen species (ROS). Moreover, when the 2 antioxidant substances were given in combination, LA worked at a 100-fold lower concentration and ALC worked at a 1000-fold lower concentration, as compared to when the substances were given individually. Given the fact that mitochondrial dysfunction and oxidative damage are significantly involved in the pathogenesis of Parkinson's disease, these results are promising. The authors conclude, "This study provides important evidence that combining mitochondrial antioxidant/nutrients at optimal doses might be an effective and safe prevention strategy for PD."

Alpha-Lipoic Acid, som er en antioxidant, kan skaffes her:
http://www.supersmart.com/en--Antioxida ... 0-mg--0291

Acetyl-L-Carnitine, som er en aminosyre, kan skaffes her:
http://www.supersmart.com/en--Amino-aci ... 0-mg--0349

Det kunne da være værd at prøve ?

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