Kan indtagelse af Liponsyre og Carnitine forhindre Parkinson
Fra dette link:
http://www.ncbi.nlm.nih.gov/pubmed/1862 ... t=Abstract
Og fra denne artikel kan det læses, at Liponsyre og Carnitine formodentlig har en effekt på Parkinsons Sygdom.
Topic: Alpha-Lipoic Acid and Acetyl-L-Carnitine in the Prevention of Parkinson's Disease
Keywords: PARKINSON'S DISEASE - Alpha-Lipoic Acid, R-Alpha-Lipoic Acid, Lipoic Acid, Acetyl-L-Carnitine, L-Carnitine
Reference: "Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease," Zhang H, Jia H, et al, J Cell Mol Med, 2008; [Epub ahead of print]. (Address: Jiankang Liu, PhD, Institute for Brain Aging and Dementia, University of California, 1261 Gillespie Neuroscience Research Facility Irvine, CA 92697-4540, CA, USA. E-mail: j.liu@uci.edu ).
Summary: In a study involving a rotenone-induced cellular model of Parkinson's disease (PD), 4-week pre-treatment with a combination of R-alpha-lipoic acid (LA) and acetyl-L-carnitine (ALC) was found to protect SK-N-MC human neuroblastoma cells against rotenone-induced mitochondrial dysfunction, oxidative damage, and accumulation of alpha-synuclein and ubiquitin, and to increase mitochondrial biogenesis and decrease production of reactive oxygen species (ROS). Moreover, when the 2 antioxidant substances were given in combination, LA worked at a 100-fold lower concentration and ALC worked at a 1000-fold lower concentration, as compared to when the substances were given individually. Given the fact that mitochondrial dysfunction and oxidative damage are significantly involved in the pathogenesis of Parkinson's disease, these results are promising. The authors conclude, "This study provides important evidence that combining mitochondrial antioxidant/nutrients at optimal doses might be an effective and safe prevention strategy for PD."
Alpha-Lipoic Acid, som er en antioxidant, kan skaffes her:
http://www.supersmart.com/en--Antioxida ... 0-mg--0291
Acetyl-L-Carnitine, som er en aminosyre, kan skaffes her:
http://www.supersmart.com/en--Amino-aci ... 0-mg--0349
Det kunne da være værd at prøve ?
http://www.ncbi.nlm.nih.gov/pubmed/1862 ... t=Abstract
Og fra denne artikel kan det læses, at Liponsyre og Carnitine formodentlig har en effekt på Parkinsons Sygdom.
Topic: Alpha-Lipoic Acid and Acetyl-L-Carnitine in the Prevention of Parkinson's Disease
Keywords: PARKINSON'S DISEASE - Alpha-Lipoic Acid, R-Alpha-Lipoic Acid, Lipoic Acid, Acetyl-L-Carnitine, L-Carnitine
Reference: "Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease," Zhang H, Jia H, et al, J Cell Mol Med, 2008; [Epub ahead of print]. (Address: Jiankang Liu, PhD, Institute for Brain Aging and Dementia, University of California, 1261 Gillespie Neuroscience Research Facility Irvine, CA 92697-4540, CA, USA. E-mail: j.liu@uci.edu ).
Summary: In a study involving a rotenone-induced cellular model of Parkinson's disease (PD), 4-week pre-treatment with a combination of R-alpha-lipoic acid (LA) and acetyl-L-carnitine (ALC) was found to protect SK-N-MC human neuroblastoma cells against rotenone-induced mitochondrial dysfunction, oxidative damage, and accumulation of alpha-synuclein and ubiquitin, and to increase mitochondrial biogenesis and decrease production of reactive oxygen species (ROS). Moreover, when the 2 antioxidant substances were given in combination, LA worked at a 100-fold lower concentration and ALC worked at a 1000-fold lower concentration, as compared to when the substances were given individually. Given the fact that mitochondrial dysfunction and oxidative damage are significantly involved in the pathogenesis of Parkinson's disease, these results are promising. The authors conclude, "This study provides important evidence that combining mitochondrial antioxidant/nutrients at optimal doses might be an effective and safe prevention strategy for PD."
Alpha-Lipoic Acid, som er en antioxidant, kan skaffes her:
http://www.supersmart.com/en--Antioxida ... 0-mg--0291
Acetyl-L-Carnitine, som er en aminosyre, kan skaffes her:
http://www.supersmart.com/en--Amino-aci ... 0-mg--0349
Det kunne da være værd at prøve ?
Kommentarer
Jeg får en del spørgsmål fra andre parkinsonpatienter om Liponsyre og var derfor inde og surfe på Internettet.
Liponsyre er både en antioxidant og et afgiftningsmiddel ved tungmetalforgiftning.
Nedenstående udsagn giver håb (set med mine øjne) for os parkinsonpatienter, (selvom forskningen er foretaget på dyr).
“Results with previous studies suggest that R-Lipoic acid may be an effective neuroprotective agent in age-associated neurodegeneration.”
Link: http://www.ralapure.com/parkinsons.asp?page=2
Der er mere viden om Liponsyre på disse links:
http://www.ralapure.com/
http://www.ralapure.com/all.asp?page=1
Liponsyre kan også skaffes her:
www.supersmart.com
http://www.supersmart.com/en--Antioxida ... 0-mg--0301
God læselyst